منابع مشابه
Beyond antigens and adjuvants: formulating future vaccines.
The need to optimize vaccine potency while minimizing toxicity in healthy recipients has motivated studies of the formulation of vaccines to control how, when, and where antigens and adjuvants encounter immune cells and other cells/tissues following administration. An effective subunit vaccine must traffic to lymph nodes (LNs), activate both the innate and adaptive arms of the immune system, an...
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To increase the awareness of society to the challenges of global food security, we developed five contrasting global and European scenarios for 2050 and used these to identify important issues for future agricultural research. Using a scenario development method known as morphological analysis, scenarios were constructed that took economic, political, technical, and environmental factors into a...
متن کاملFormulating the Future Research Agenda for Postexposure Prophylaxis for HIV: Methodological Challenges and Potential Approaches.
BACKGROUND During a World Health Organization-convened Guideline Development Group meeting, recommendations for postexposure prophylaxis (PEP) for human immunodeficiency virus were made and research gaps identified. METHODS We used the PEP clinical management pathway and the Grading of Evidence, Assessment, Development and Evaluation (GRADE) system as a framework to formulate future research ...
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CIOs and other senior executives face the challenge of how to handle the opportunities and risks of digital transformation. We believe that firms need a standalone digital transformation strategy that signposts the way toward digital transformation and guides managers through the transformation process resulting from the integration and use of digital technologies. A digital transformation stra...
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ژورنال
عنوان ژورنال: American Zoologist
سال: 1994
ISSN: 0003-1569
DOI: 10.1093/icb/34.1.165